B

Bioinformatics

This project explores and implements robust relational data models for efficiently storing and querying large-scale genetic Variant Call Format (VCF) data. Leveraging PostgreSQL, we present and evaluate eight distinct schema designs, demonstrating how traditional relational databases can offer competitive performance, scalability, and full database management system (DBMS) features for complex genomic workloads, complementing specialized tools like BCF Tools and TileDB-VCF.